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Archive for the ‘Special situations’ Category

Yasmin, Yaz and Other Drospirenone Contraceptives: Risk for VTE

| Uncategorized, Women and blood clots | Comments Off on Yasmin, Yaz and Other Drospirenone Contraceptives: Risk for VTE

It has long been known that estrogen-containing birth control preparations (pill, patch, ring) increase the risk for DVT and PE (venous thromboembolism = VTE).  This risk is partially due to the estrogen.  However, part of the risk is also due to the type of progestin in these preparations. Read the rest of this entry »

Pregnancy and Venous Thromboembolism: Prevention, Diagnosis, Treatment

| Uncategorized, Women and blood clots | 1 Comment »

A new guideline about the prevention, diagnosis, and treatment of DVT and PE associated with pregnancy was published today by ACOG (American College of Obstetricians and Gynecologists) in its respected series of Practice Bulletins.  The bulletin includes detailed reference to thromboprophylaxis in pregnant women with thrombophilia. Read the rest of this entry »

Pregnancy Loss and Thrombophilia

| Acquired risk factors, Anticoagulants, Heparin, Inherited, LMWH, Therapy, Thrombophilias, Uncategorized, Whom to test, Women and blood clots | 1 Comment »

How common is pregnancy loss? What are the causes?

Pregnancy loss  in the general population is common. Most losses occur in the first trimester. As many as 5 % of women have 2 or more early losses; 1-2 % have 3 or more early losses [ref 1]. Well established risk factors for pregnancy loss are: (a) advanced maternal age, (b) anatomic uterine abnormalities (fibroids, septum, etc), (c) chromosome abnormalities of fetus, mother or father, (d) comorbid diseases of the mother (endocrine, immunologic).  The acquired antiphospholipid antibody syndrome is also a risk factor for pregnancy loss. The role of inherited thrombophilias contributing to pregnancy loss is less clear. Read the rest of this entry »

Incidentally Discovered DVT, PE or Other Clots

| Cancer and blood clots, Clots in unusual locations, Deep Vein Thrombosis (DVT), Pulmonary Embolism, Uncategorized | 3 Comments »

General comments

CT or MRI scans will occasionally detect an incidental iliofemoral DVT, PE or intra-abdominal thrombosis (IVC, portal, splenic, mesenteric or renal vein). This is particularly common in cancer patients undergoing staging CT scans. When such an incidental, asymptomatic venous thromboembolism (VTE) is discovered, the question arises whether the patient should be treated with anticoagulants or not. Read the rest of this entry »

Progestin-only Contraceptives and Thrombosis

| Deep Vein Thrombosis (DVT), Pulmonary Embolism, Thrombophilias, Uncategorized, Venous Clots, Women and blood clots | 2 Comments »

Background

It is well known that combination contraceptives (containing estrogens AND progestins) increase the risk for venous thromboembolism (VTE). Relatively few data, however, have been published on progestin-only contraceptives, so that until recently it was not clear whether they increase the risk for venous thromboembolism (VTE) or not. Read the rest of this entry »

Heavy Menstrual Bleeds on Anticoagulants – Treatment Options

| Anticoagulants, Bleeding, Uncategorized, Women and blood clots | Comments Off on Heavy Menstrual Bleeds on Anticoagulants – Treatment Options

Evaluation
Anticoagulants often increase the amount of bleeding during menses and sometimes the number of days that a woman bleeds. However, this does not happen in every woman.  In general, the more vaginal bleeding a woman has, the more cramping she experiences. Since warfarin may increase the vaginal bleeding Read the rest of this entry »