Education Blog for Healthcare Professionals

Pregnancy, Breastfeeding – Safety of Various Anticoagulants

Stephan Moll, MD writes… LMWH (low molecular weight heparin) is the preferred anticoagulant in the pregnant patient. LMWH and warfarin are safe in the woman who is beast-feeding.

Rivaroxaban (Xarelto), dabigatran (Pradaxa) and apixaban (Eliquis) should not be used during pregnancy or while breastfeeding.

A detailed summary about the safety of the various anticoagulants during pregnancy and while breast-feeding, based on the ACCP 2012 guidelines [ref], can be found here. 

Click on image above for a detailed summary about the safety of each anticoagulant during pregnancy and breastfeeding


Bates SM, Greer IA, Middeldorp S et al. VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST 2012; 141(2)(Suppl):e691S–e736S.


Disclosure:  I have consulted for Janssen and Boehringer-Ingelheim. 

Last updated: Jan 23rd, 2014

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