Education Blog for Healthcare Professionals

LMWH and Epidural Catheters – FDA Recommendations

Stephan Moll, MD writes… The FDA published today a drug safety recommendation to decrease bleeding and paralysis risk for patients receiving epidural catheters and being treated with LMWH  (detailed FDA report is here).  While in many parts of the document the FDA talks specifically about enoxaparin, the communication states that “these new timing recommendations….. will be added to the labels of anticoagulant drugs known as LMWH, including Lovenox and generic enoxaparin products and similar products”.  The recommendations are as follows:

A.       Placement of a catheter

    • Wait ≥ 12 hours after a prophylactic dose
    • Wait  ≥ 24 hours after a full dose (enoxaparin 1 mg/kg twice daily or 1.5 mg/kg once daily)

B.      Removal of a catheter

    • Wait ≥ 12 hours after a prophylactic dose
    • Wait  ≥ 24 hours after a full dose (enoxaparin 1 mg/kg twice daily or 1.5 mg/kg once daily)

  C.      Restart enoxaparin after catheter removal

    • No sooner than 4 hours after catheter removal.

 

Disclosure:  No financial conflict of interest.

Last updated:  Nov 7th, 2013

Tags: , ,

This entry was posted by Clot Connect on at and is filed under Bleeding, LMWH, Uncategorized. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.

Comments are closed.