Education Blog for Healthcare Professionals

Arixtra (Fondaparinux), Generic

“Is the generic version of Arixtra as safe and effective as brand Arixtra?”  Answer: “Yes”.

The FDA evaluated and approved generic fondaparinux made by Dr. Reddy’s Laboratories Ltd. on July 11, 2011 (announcement about approval here).  Fondaparinux (Arixtra) is a once daily s.c. anticoagulant and can be given

  • for DVT prevention at a lower, i.e. prophylactic, dose, or
  • for treatment of DVT and PE at a higher, i.e;. at full therapeutic dose overlapping with warfarin in the first few days of warfarin initiation, or
  • as an alternative to warfarin in patients who have had recurrent VTE in spite of adequate INRs on warfarin (i.e. in patients in whom warfarin has failed).

Disclosure: I have no conflict of interest relevant to this post.

Last updated: Sept 26th, 2011

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