A discussion of PFO and paradoxical embolism, written for patients, is available on the Clot Connect Patient blog- connect here. The health care professional can refer his/her patient to the information on PFO in that blog . The blog also contains images suitable for patients to understand the etiology of paradoxical embolism:
case scenario with response request:
36 yo white male, cryptogenic stroke and PFO and Factor V Leiden mutation; after closure of PFO, would you consider life long anti-coagulation? and if so, aspirin or coumadin?
Stephan Moll says:
To prevent recurrent stroke, I would give long-term aspirin; clearly not an anticoagulant. However, if there is evidence of a DVT, a decision on use of anticoagulants needs to be made to prevent recurrent VTE, and that decision would, of course, depend on whether the DVT was associated with a major transient risk factor or not. The fact that this patient has heterozygous factor V Leiden would likely not influence any of my decision making.